HIV infects and prevents the proper function of neurons

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January 2015 neurons ___Neurotropism

Among neuropathies, dementia symptoms appear faster than in Alzheimer's.

Thinking man

For being "neurotropic", That is, liking neurons and the central nervous system, acquired immunodeficiency virus - HIV wreaks havoc in the brain of patients HIV positive. He not only infects, it also prevents the proper function of the neuron (cell responsible for passing nerve impulses) causing symptoms of dementia call the HIV or dementia complex AIDS. According to Dr. Denis Bichuetti neurologist, it is a neurological impairment caused by pp anonymous HIV, Which destroys the glial cells responsible for nutrition and survival of nervous tissue. The consequences can be loss of memory, reasoning, motor coordination and even hallucinations and delusional idea. The framework evolves slightly faster than Alzheimer's disease.

Besides dementia, there are a number of neurological disorders associated with HIV being caused by various opportunistic infections (taking advantage of the weakened immune system caused by HIV). These include tuberculosis, cryptococcosis, toxoplasmosis and PML (progressive multifocal leukoencephalopathy). The latter is an infection caused by the JC virus and its main symptoms are motor loss, seizures and altered behavior, all occurring subacute form (in weeks).

To detect the disease - The techniques to diagnose neurological impairment by HIV do not differ much from those used conventionally: Computed Tomography, Magnetic Resonance, LRC collection, etc. The difference is made in the use of laboratory techniques called serology and PCR (quantitative or viral load), which identify specific infectious agents when the clinic is frustrated and much earlier than cultures, which can take days or weeks. Brain magnetic resonance imaging is another necessary test that can show variable changes and even show scars, but the result must be associated with the clinical picture, laboratory and imaging results, all added up. [14]

Progression and treatment of dementia

In contamination by HIV, neurological aggression occurs early. But clinical manifestations (symptoms), usually occur later. For the prevention of diseases, good control of viral load and cells is essential CD4 (the defense cells attacked by HIV and destroyed for their multiplication in the body). "The best treatment is the HIV, performed by an infectologist. When the symptoms of neurological diseases appear, it is also necessary to follow up with a neurologist to treat the symptoms, "says Dr. Denis.

Author or Writer Source: PriscilaDadona and Silvia Alves

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