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Life as an elite controller HIV

June 23, 2015, PorRodney Rousseau

After being diagnosed with HIV in 2013, my first round of laboratory monitoring indicators showed an undetectable viral load, and my CD4 count - a measure of immune health, above 900 / mm3 (typical of healthy adults with counts CD4 between 500 and 1.200 cells / mm3). I remember my nurse have been surprised with the results and ordered another round of tests to make sure it was not a lab error.

That's when the second round of tests came back, with similar results, he told me I could be an elite controller.

Did you know that the higher estimate, about 5% of people living with HIV maintains a CD4 cell count normal (above 500 cells / mm3) for eight years or more even in the absence of antiretroviral therapy?

Researchers call these people "non-progressors long term" since they remain asymptomatic or have a large delay in disease progression over the course of HIV infection.

RBCA smaller subset of people with HIV, about 1% -consegue suppress viral replication and to maintain the CD4 count higher than expected. Elite controllers, as we are called, keeps their viral loads undetectable even in the absence of antiretroviral therapy, although some small increases viral "fruitful", has been documented in some individuals.

Some may be jealous because I have been able to escape the daily struggle of HIV, antiretroviral therapy (and side effects) that most people with HIV have to bear with patience in their lives. But I can not say I felt lasting relief, so to speak, on my status as an elite controller.

After finding out that I was an elite controller, I felt a lot of confusion. I knew what an elite driver, but does not translate to know what it is, when it is actually a.

I was not new in the HIV world I had previously been a volunteer working with the community of homeless people with HIV that was offered to those who wish to pursue a career as a researcher in microbiology and HIV, but I realized that I knew nothing about what was happening in my own body.

I would like to start antiretroviral therapy (ART) immediately. I wanted to have a proactive attitude, so that I could feel in control of my own health.

When I was told that there was really no compelling reason for me to start ARV treatment, I had mixed feelings. I was relieved not to have to take one or two or five pills a day. But I also felt a lack of control over my own condition. How would I take care of myself? There was nothing I could do?

priceI began to find out what is an elite controller, and not have to take anti-retroviral drugs,can be priced Despite the ability to suppress HIV replication, elite controllers often suffer from chronic immune activation and inflammation over a longer time than seropositive "normal" levels and higher than experienced by people with HIV who control their viral load with HAART. While the cause of inflammation is not well understood, it is connected to all kinds of health problems such as, for example, cognitive conditions and cardiovascular diseases.

Note the Soropositivo.Org Editor: I suggest a pause in your reading, to watch this video and comprender, rather, what it is the immune response and how this could translate into SUFFERING for that person with this supposed "advantage". But if you, like most people here do entam leave the video and then, nothing you will be asked for it, neither in this nor in the other world

If voc6e saw the video realized, too, that God is wonderful, right?

One study showed thatelite controllers has a higher hospitalization rate for cardiovascular disease than people on antiretroviral treatment, they have suppressed their viral loads and also people on antiretroviral treatment with a detectable viral load. Cardiovascular events were, from a statistical point of view, the cause of about 30% of hospital admissions of elite controllers, but less than 15% for people taking antiretroviral drugs.

I'm just in my "twenties" and already started to worry about how these things affect me in the medium and long term. For me, being a person "ART-free does not seem a benefit under any circumstances, given that it only means that my health may still be at risk, despite the absence of need of ART.

At this point, "research has not yet defined "if Elite controllers may get some benefit by taking standard ART.Em a small study, with 16 elite controllersThey found that treatment with HAART 24 weeks reduced some measures of immune activation and inflammation (proteins "biomarkers") that are associated with mortality in people with HIV. Residual HAART has also reduced the number of anti-HIV antibodies and viruses persist in blood and intestinal tissue levels of elite controllers.

But because this study had a small sample size and not beyond 24 weeks? More monitoring is needed to see if these types of changes are clinically relevant, and make a significant difference in the lives and health of elite controllers?

A recentreview in The Journal of Infectious Disease this yearit was concluded that we need better data before firming treatment recommendations for doctors on how to treat Elite Controllers. This time if, and how to prescribe antiretrovirals to Elite Controllers is a subject that "lies firmly in the category of" expert opinion. "

Manage my HIV infection is a constant correction process.

I commit to constantly engage me with the research that can inform me what is the best way to take care of my health. The scientific community is constantly correcting and expanding what we know about HIV and elite controllers. I read everything I can, and I'm not afraid to ask questions, and do my homework with my health allows me to actively participate in decisions made about my state of health. Constant correction means that someday I may need to start antiretroviral therapy, or perhaps some other drug.

Now, which means I'm just trying to live a healthier life that I can, as I did before being diagnosed with HIV: practicing physical exercise, healthy eating and fighting for a balanced life.

Rodney RousseauHe is a gay man living with HIV HIV immunology complete a graduate degree in Toronto, Canada. Rodney is an activist and member of the community work with a particular interest in the impact of basic science and clinical research and interdisciplinary understanding of HIV as a complex health problem. Rodney is also an author with Translated from Original inLife as an HIV Elite Controllerby Claudio Souza. This work would not come out satisfactorily without the insuplantáveis ​​loans Mara Macedo Review.


Selected sources.

Crowell, T. et al.Hospitalization rates and Reasons Among HIV elite controllers and persons with medically controlled HIV infection. Journal of Infectious Diseases.UNTIL 2014. Karris, M. and Haubrich, R.Antiretroviral therapy in elite controllers: Justified or premature? officer infectious diseases.UNTIL 2014. Krishnan, S. et al.Evidence for innate immune system activation in HIV-infected type 1 elite controllers. Journal of infectious diseases.UNTIL 2014. -Saag, M. and Deeks stated, S.How do HIV elite controllers do what They Do? Clinical Infectious Diseases.YEAR 2010. <p style = "text-align: left;">
About Claudio Souza do Soropositivo.Org (506 articles)
Yes, this is the photo of me! My niece asked me to put this picture on my profile! .... I had here a description of me that one person described as "irreverent". This is really a euphemistic way of classifying what was here. All I know is that an "NGO" which occupies a building of 10 floors has established a partnership with me, and I have the logs of the partnership time, which was more a vampirism because for each 150 people leaving my site, clicking on them, there was, on average, one that came in. WHEN I ENTERED AND ENTERED

2 comments Life as an elite controller HIV

  1. Hello, is that an elite controller changes the immune time window, the time to seroconversion?

    • It seems to me, and I rarely mistaken, that u are trying to find a way to deny or disown a nonreactive examination.
      U are mistaken. The person who is elite parent creates a much greater amount of antibodies than a normal person +++ +++
      And, do not think that if you were an Elite Controller you would be there in a good way. Usually elite controllers have so many unoccupied antibodies that they come to live as unoccupied.
      Oh you ask me:
      - "How to live the unemployed antibodies"? And I answer:
      - "Making riot", forcing you to attend the clinic and health center with greater fidelity than most people
      And if, I'm not mistaken, you've read about it, in this text .... Or should I assume that you found the beginning of the text and came straight to the comments? ...
      Make your tests, if not already done so, and if you fulfilled the time iunológica window machete. And then there was fulfilling the window period that is the link back there, and gave negative, accept it and learn the lesson:
      Your life is worth more than More than one fuck

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