HIV can become resistant to drugs used to treat it. This is because HIV changes, or mutates, slightly every time it reproduces itself. Some of these are mutations in the virus that is targeted by anti-HIV drugs and may mean that this anti-HIV drug does not work well against some strains (types) virus.
How to reduce the risk of resistance
The most important thing you can do to reduce your risk of developing drug resistance is to take your HIV treatment seriously and take it properly. Take antiretroviral drugs properly is called Accession, And it has been shown that you need to take all, or almost all, their antiretroviral doses correctly so that your treatment is the best the best job opportunity (Translator's note. Talking to a Nurse anum center specializing in her AIDS . me whispered that the goal is 95% When el realized that I began to reckon she explained, "You can miss a single dose in the month and look there!" So I say Look lá.e not miss any..
Good adherence includes taking all your doses at the right time, in the right quantity and the right way (eg with or without food as directed). It is also important to make sure you avoid taking your antiretroviral drugs with other medicines or drugs that may interfere with the way your body processes them.Seu infectious or pharmacist will check it once it's important that you tell them about anything you may be taking.
Poor adherence can mean that there is not enough medicine in your body to fight HIV, and this may mean that the strains of the virus that are resistant to anti-HIV drugs can reproduce and become the main strain of HIV in your body.
How to get toviral load comundetectable levels means you have a very low risk of developing anti-HIV drug resistance. Therefore, the goal of HIV treatment is an undetectable viral load. Undetectable viral load is usually defined as below 40 copies / ml. Until recently, this was the lowest detectable level more tests used in routine monitoring of viral load. Now there are some ultra-sensitive tests that can measure down 20 copies / ml.
Also, people whose viral load remains high or rebounds whilst taking anti-HIV drugs may still experience a lasting increasethe count CD4 and the delay of disease progression, although the reason why this occurs are not well understood. Although resistance is a reason for the return of the viral load is not the only reason.
About 10% of new infections with HIV virus that is resistant to one or more anti-HIV agents. This can limit your options in antiretroviral treatment.
The results of these tests can helpinfectologist choose the Antiretroviral Therapy scheme with the best chance of working against HIV in your case. Translator's note: You who read me now wondering if may or may not be infected with HIV should be thinking, "What if I have a resistant strain to easier remedies (with fewer side effects) of taking? What if my infection is by a virus resistant to all drugs? "It is time to put a little more than yam within this his head and use condoms in all sexual relations?
If you develop resistance to antiretroviral drugs, then there is a chance that you have also developed resistance to other drugs that you have not taken, if they work against HIV in a similar way. This is called cross-resistance.
Change treatment due to the resistance
If the viral load increased is generally recommended that youSwitch to an entirely new combination of anti-HIV drugs. The results of theirResistance Testwill help guide the choice you and your doctor.
New types of anti-HIV drugs have been developed called entry inhibitors and integrase inhibitors. They work differently to the measures of other antiretroviral drugs and that means they can be important new treatment options for people who have had a lot of anti-HIV drugs in the past.
Michael Carter, Greta Hughson
Published: 13º 2012 MARCH