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More than two-thirds of young adults with HIV could present neuro-cognitive impairment-revised


I often wonder if I am even normal ...

According to a study by the US Health researchers from the National Institutes (NIH, in English) and published inJournal of Adolescent Health (Journal of Adolescent Health in free translation from English)More than two-thirds of young adults with HIV would present asymptomatic cognitive deterioration that, while not interfering with the daily activities, could affect several cognitive domains such as memory or motor skills. The risk of developing such complications would be reduced while maintaining good control of infection and to avoid heavy drinking.

The neuro-cognitive deterioration associated with HIV was an important subject of study in recent years (seeLa Noticia delDía 16 / 07 / 2013), Given its highincidenceand how it can affect the quality of life of those who suffer. However, until this study, this complication had not been investigated in young adults. Whereas this collective is affected by more than a third of new infections, search the presence of neuro-cognitive impairment in this age group was an important social need.

To clarify this point, researchers with the participation of 200 young adults with HIV, aged 18 and 24 years. Participants were not in treatmentantiretroviraland had received the diagnosis of infection during the two years prior to its inclusion in the trial.

All participants took a battery of tests that assessed various neuro-cognitive areas such as memory, attention, different motor skills (coordination, balance, etc.) and verbal ability and reading. We also included questions about the use of recreational drugs and healthy habits.

67% of the study participants had neuro-cognitive impairment, which in 96% of cases were asymptomatic.The worst affected areas were memory and fine motor skills.

Na multivariable analysisconducted by researchers, Factors such as having a low number ofCD4Have been growing period after diagnosis of infectionCancer Cell HIV and high alcohol consumption was associated independently and significantly to the development of neuro-cognitive impairment.

The neuro-cognitive functions are one of the most important aspects for the evaluation of a person's quality of life. In the specific context of HIV infection, cognitive ability has special importance, considering the need of own health care and continuity of antiretroviral therapy, which often need to follow complex agendas. If memory loss occasioned him a badaccessionto treatment, there is a risk of loss of control of HIV infection, a fact that, in addition to endangering the health of the individual, decrease the number of CD4, one of the risk factors that may worsen the neuro-cognitive impairment observed in the study .

The results of this test are of particular concern because, if neuro-cognitive problems are observed in young adults in such a high proportionEven if the majority are asymptomatic,do not know its long-term evolution, and its intensity could increase. Thus, it will be important to determine accurately the causes that favor this deterioration and search therapeutic interventions that are able to stop it and hopefully reverse it.


Source:HIVandHepatitis. Reference: Nichols SL, Bethel J, Garvie PA, et al. Neurocognitive Functioning in Antiretroviral Therapy-Naive Youth With Behaviorally Acquired Human Immunodeficiency Virus. Journal of Adolescent Health. August 21, 2013 (Epub ahead of print).

Francesc Martínez

Translator Rachel Cirne EN <> ESP

About Claudio Souza do Soropositivo.Org (506 articles)
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