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Bacterial vaginosis and the efficacy of oral PReP

The efficacy of oral PReP

PrEP Oral and bacterial vaginosisResearch on PrEP Oral Presented at the Conference on Retroviruses and Opportunistic Infections last month in Seattle found that the efficacy of oral pre-exposure prophylaxis (PReP) for women was not affected by bacterial vaginosis (BV).

Excessive growth in the vagina of atypical microbes.

The efficacy of PrEP in the PrEP Partners study was not significantly different in women with and without bacterial vaginosis.

This excludes Vaginal bacteria as a possible cause of lower effectiveness of oral PrEP in some studies among women compared to studies of men who have sex with men.

However, another study has shown that tenofovir concentrations were lower in women with bacterial vaginosis who used a microbicide gel - corroborating the difference in efficacy already observed in theStudy tenofovir gel CAPRISA 004 (This link leads to an automatic translation of the referred text).

Studies are being conducted to find out if bacterial vaginosis has affected the effectiveness of vaginal rings.

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