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CD4 cells - Macrophages - T cells

CD4 Cells - Macrophages - T Cells

Editor's note: The indications on this page for the beginning of HAART are wrong and it was a problem to expect health declined to such an extent (today I see how disgusting it was) that we were facing life risks or being very close to passing .

The START study confirmed that antiretroviral therapy (ART) should be started as soon as the diagnosis is made. It remains here as a living document of the errors that Cietists have commented on and God knows how many people have died wretchedly in such an irrational way.

CD4 cells or macrophages (sometimes known as T-cells or helper cells) are the white cells that organize the immune response of your body; if your system 1immune system was compared to an army - and this nomenclature would suit him very well - these cells could be known as the generals of his immune system.

The counting of these cells is to measure the amount of them, the CD4 cells, found in a milliliter of blood (a very small portion of the blood), and not your whole body, as you might think; this analysis parace be insufficient and, however, is more than enough to analyze the condition of your immune system. Your doctor probably will refer to them as a number; for example, 498.

The count CD4 cells in a person not infected with HIV and may vary between 500 1500. However, CD4 counts can vary greatly from individual to individual. Your own count CD4 can vary greatly due to many factors, for example:

  • Women generally have higher scores than men CD4 (about 100).
  • Count CD4 cells usually oscillate up and down depending on your menstrual cycle.
  • Oral contraceptives tend to lower the count CD4 women.
  • Smokers tend to have a count of CD4 than nonsmokers (about 140).

However, none of these factors seem to influence the immune response in humans.

Only a small proportion of cells are CD4 in your bloodstream. The rest of them remains between organs such as spleen, and lymph nodes. Variations in CD4 count may occur due to such migration between the blood and body tissues.

So, rather than give too much importance to a single examination. The ideal is to make a measurement on the count CD4 in small intervals, and these intervals are much smaller, the better. And yet, if you are not feeling well or are having an active infection such as herpes or flu, you'd better ask your doctor to delay a little collection of material until you feel better. If you get a very different result than usual, and no matter whether it be for better or for worse, ask your doctor to repeat the test to see if there was a mistake in the lab.

Soon after HIV infection, your score will probably CD4 fallen sharply before stabilizing. Even when you feel well and there is no apparent sign of HIV infection, millions of cells of this type are being invaded and lost every day, and millions more are being produced to replace them. Without treatment, an HIV positive person will lose gradually, and these cells will, on balance, a decrease in cell count CD4 and another fall, this, the quality of the immune response.

A score of between CD4 200 500 and indicates that some damage has been suffered by your immune system.

It is particularly important to monitor your score CD4 until it approximates 350 cells per milliliter of blood

Monitoring cell count CD4

CDd count
So start with a syringe, a sting (which, for me, I take stings every day since 2012 - Clexane-) shit. And this tube with san ... I say, "material" for the complex verification of how many CD4 cells are present with every milliliter of Blood. Above 350 is good, above 500 Ó.MOUNT !!!

It is recommended that you take two exams count CD4 if you are newly diagnosed with HIV infection. These results serve to provide a basis on their health situation, so you and your doctor can monitor future changes. These tests usually occur the first time you visit the infectious disease and, three months later, when you make your return visits.

If you have a relatively high without symptoms CD4 count and are not taking antiretroviral drugs, their count CD4 will be monitored every three or four months, or even every six months, if it is very high.

However, if your count is dropping fast CD4 or approaching levels where it is recommended to start treatment (currently in 350 for most people) or if you are participating in a clinical trial, your doctor may suggest, and will be clever of you to accept that your count CD4 be monitored more frequently.

After you start your treatment with antiretroviral drugs, you will often count a new CD4 about a month after you start treatment, and every three months. Once you have your undetectable viral load (see Viral) and its CD4 count starts to rise, your doctor may suggest that the count is done every three months and then every six months. You can have the focus of your expectations, there will be an increased frequency of testing if your score stop climbing if you show symptoms or not feeling well.

The monitoring its count CD4 will help you and your doctor in making important decisions in caring for your health in general and HIV treatment, do not let go of it

Count CD4 above 350 - monitoring and early treatment in some circumstances.

If your score is above CD4 cells 350 and you are without symptoms, you probably do not need to start treatment now. But his count CD4 be maintained with regularity every six months. When your count cd4 start approaching 350 may want to monitor this more closely, every three months, for example, or even smaller intervals.

In some situations your doctor may determine that you begin treatment with antiretroviral drugs even if your score is above 350. These options include:

  • IF you are coinfected with hepatitis B or C, for liver diseases worsen if the count is low CD4.
  • If you have kidney problems.
  • If you are in treatment for cancer.
  • If you have a relatively advanced age (over 50, for example).
  • If you want to get treatment, why be concerned about the possibility of transmitting HIV to someone (treatment significantly reduces the possibility of transmitting the virus).
  • If you are ill because of HIV infection.
  • In some cases, it is clear that you recently acquired HIV.

Count on CD4 350 - Starting HIV treatment

Immunologic Window and CD4 Cells
The bluish part of this photo is the surface of the CD4 cell and these green spots are "virions", or, as you like, HIV. This photo is in the public domain and can be found on wikipedia

If your count CD4 drop to or near 350 350 is usually common to start HIV treatment. It has been shown that starting treatment with counts CD4 around 450 brings a number of advantages that started with CD4 in lower scores.

The immune system recovers more easily and quickly when treatment starts with counting CD4 around 350.

Starting treatment with counting CD4 around 350 creates a condition where you hardly get sick because of HIV. It is also shown that starting HIV treatment on this count, reduces greatly the likelihood of you developing serious diseases such as kidney or liver diseases, as well as some cancers.

Your doctor will talk with you about the start of treatment when the count CD4 approach 350. At this stage of treatment you will have more frequent exams CD4.

Count on CD4 200 or below - immediately start HIV treatment and prophylaxis for other diseases

If your count CD4 Stow in 200 or below it is essential that your doctor start HIV treatment immediately. A count of CD4 these levels is an indication that you are at serious risk of developing serious diseases known as opportunistic diseases.

Therefore, you should also start taking other medications such as antibiotics, to prevent the emergence of these diseases; this is called chemoprevention. The type of chemoprophylaxis you will get will depend on your score CD4. Only your doctor, not you, is able to tell when you can stop safely to chemoprophylaxis. This occurs generally when the count rises above CD4 200 and remains, while above this.

For example: You may receive antibiotics (such as Bactrim or Dapsone) to guard against PCP, a dangerous type of pneumonia.

You may have to do other tests to assess their clinical / medical condition. Issso may include tests to assess illnesses and conditions, and may include tests for tuberculosis (TB). In countries like Brazil, with high rates of tuberculosis, you will be tested anyway

His count CD4 when you are being treated for HIV

CD4

Once you begin treatment for his HIV viral load will begin to fall and is expected to count CD4 climb gradually. The rate of growth varies from individual to individual and depends on many factors. In some people are required months and sometimes years for the count of cells cd4 rise to normal levels for the age of the person. In general, the lower the viral load is when you start treatment, the longer it takes for the immune system is completely recompose. But it's good that you understand that even the slightest change in your CD4 count, up, brings huge benefits to your health

Your doctor will monitor your viral load and count your CD4 for three months until it normalizes. Once your viral load becomes undetectable and his CD4 cell count starts to rise, your doctor may suggest (and it is up to you to accept or not) that the monitoring of these paths pass for longer periods, for example, every six months ..

Percentage of CD4

In addition to counting and monitoring the count CD4 some doctors sometimes make the measurement of the ratio of how many white cells are CD4 (There macrophages, TK, CD8 cells and others, all with definite and important functions for your health). Called CD4 percentage of cells. Although this system mensuramento white cell is not the most appropriate for monitoring the health of the immune system of adults, there are situations where this measurement is useful.

For example. If your count is very different from CD4 percentage CD4 can be an indicator of other health problems

Another situation where this comparison is useful when there is a wide variation between the count and the percentage of CD4 CD4 because there may be some kind of lack of harmony in these paths and this can be a warning sign that bigger problems may be about to occur, and thus the doctor may order additional medical tests, as for the people says, nip it in the bud.

It is very important that cd4 cell counts are done regularly.

A note from the Editor in March of 2018. Since 2017 we have done, we, people living with HIV, only the examination of viral load, since rarely, when the patient keeps with correction the most important ADHERENCE TO THE TREATMENT, WHICH SO RARELY OCCURS AN ABRUPT AND IMPORTANT FALL OF COUNTING OF CD4.

We have periodically done only the measurement of the viral load and, if it goes up, a new measurement is made, in order to effectively give notice of possible therapeutic failure or was,just a viral blipe

The Original you find here.

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The CD4 cell count is critical to early treatment of the person with HIV and person living with AIDS.
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15 thoughts on "CD4 cells - Macrophages - T cells"

  1. Initially I started being treated as soon as appeared the remedies, noting that when I was diagnosed, there was no treatment and there was, I refused to accept after three days. In mid-96 appeared to "combination therapy (said cocktail) and I started the treatment which was not soft. But because of a "treatment policy" saying it would only be necessary to enter treatment when the count reached 350 or less. My ART started, unfortunately, long after I suffered a difficult emotional shock of being supported and I just left the treatment; it lasted about six months, when the AIDS House membership group called talked a lot and convinced me to go to the House of AIDS (I just was not there anymore during these six months). There, after much conversation with a doctor and a psychiatrist I was convinced that "let me die" (this was the idea), would certainly cause pain on the person who had hurt me, but cause pain in other people who loved me tb.Eu I remember thinking nobody loves MeBut I accepted resume treatment. Made the tests I saw that my entire strategy to let me die was being unprofitable, since my CD4 was 900 adn very low viral load and there was "no need for treatment (...)." We now know, and you must go in search of this website and enter START, which is the name of a study, read the texts, print them and put them in the face of medics and demand start. treatment as this comprovadíssimo that the sooner you start treatment, the better the future of prognosis without problems. Tambeém look po statin in the search and you will see a big advantage in using statins, not only for cholesterol control and make your infectious prescribe. If u live in the state of São Paulo, they provide gratuitamente.Em other states, if eventually there is this policy, look for the Public Ministry or the Bar Association or Legal Defense and enter an injunction, duly backed by a medical report and ensure the via legal supply of the drug. Many of the remedies that I use, after 22 years with HIV because I can only use cranked the state and they fornmcem me the medicine to the living force. Tenytaram repeatedly overturn the injunction and to judge each answer is that in the Constitution: Health is a Citizen's Right and Duty of the State. They fuck them if reme'dio is expensive, u have the need for them and the governor to stop taking Dom Perignon and buy their medicines. I wanted to take and tell all the people qwue have not been very well and I'm not responde3ndo to any call on whats app. All will be answered, so I feel strong enough for that and at this time to this time I invested in vc, "Joana" was something I did because I saw a great need to wake you up

  2. Sorry I followed the link, materia on the most elite drivers not found myself in the matter! I have hiv the 11anos without taking medicine and fikei concerned about heart problems and tals

  3. If you know this person live with positive man woman are one of it's the other has to be a year when months of positive?

  4. ais've heard comments where the result came after years

    That's a lie grid! The window period is thirty days and the result came after years (sic) is because having taken "a shock", persisted in risky behavior and contracted and not confesar carelessness can, claims that it was "one sex" ... and the truth is in another

  5. I exams 2 consecutive years without going through any more risk situation, wanted to have confidence c in the test more've heard comments where the result came after years

  6. Thanks a lot for the help. I am HIV positive guys helped me understand.

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