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The Impact of Porting HIV on Aging

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The Impact of Porting HIV on Aging

"For each of the functional results, the group HIV + older individuals showed worse daily performance compared to other study groups, "the authors write. "These results suggest that advanced age may exacerbate HIV-associated disability in daily life."

Researchers believe their findings have important implications for HIV treatment. And they should focus on the early detection of functional problems and their causes.

The Success of ART Helps Drive HIV in Aging Without Developing AIDS

Thanks in part to the success of antiretroviral therapy (ART), the population living with HIV in the US and other industrialized countries is aging. US Centers for Disease Control (CDC) data suggest that a quarter of all people with HIV have more than 50 years. As they get older, they become more vulnerable to age-related disorders such as cardiovascular disease, changes in bone mineral density, and neurocognitive impairment.

Researchers assumed that the HIV infection would exacerbate the declines in daily function that are associated with these diseases of old age and aging in general.

Although "time passes for all" Porting HIV in Aging is a Complication

In others' it is refreshment

They, therefore, designed a cross-sectional study involving 103 people living with HIV and 87 controls HIV-negative. They examined the factors associated with daily and to the quality of life among minors of 40 years and those with more than 50 years.

A wide spectrum of tests was used to evaluate the operation.

Among them:

  • Instrumental activities of daily living (AIVD): financial management, purchase of groceries, cooking, transportation, shopping, medication administration and social activities planning.
  • Basic activities of daily living (BADL): cleaning, laundry, household repairs, dressing and bathing.
  • Karnofsky scores in a range of 100 (able to perform normal activities) to zero (death).
  • Questionnaires evaluating the quality of life related to physical and mental health.
  • Medical evaluation: evaluation of common comorbidities in elderly people living with HIV, including diabetes, cardiovascular disease, respiratory disease and co-infection with hepatitis C.
  • Neuropsychiatric evaluation: monitoring of neurocognitive impairment related to HIV.
  • Psychiatric evaluation: assessment of current mood and history of major depression and substance abuse.

The Continuous "Scientific Disinterest by Women"In Life Related Studies with HIV

The oldest group of people with HIV had an average age of 55 years and 71% were males. They lived with HIV hpa one time of 18 years on average.

And the mean count of the lowest CD4 cell count was 148 cells / mm3. Everyone was doing antiretroviral therapy and 90% had undetectable viral load. This group had a high prevalence of comorbidities. One room had a current major depression and half had a history of lifelong depression. More than one-third were co-infected with hepatitis C, 10% had cardiovascular disease. And yet, 15% had diagnosed of diabetes and also 5% had respiratory complaints.

There was a significant interaction between aging and o HIV in relation to the scores for IVAD (p = 0,025). As well as in AVDL scores *** (p = 0,043) and Karnofsky score (p = 0,001).

There was great impact on the prevention of HIV in Aging in relation to the impairment of cognitive functions

Factors associated with lower IADL scores for with HIV (p = 0,043), lower CD0,002 cell count (p = 4) and lack of "cognitive reserve" - ​​involvement with social activities (p = 0,023).

The gravity of ABEL ** (I tried to find the definition of it. Unsuccessfully) was associated with current depression (p = 0,007). A minor Karnofsky score for older people with HIV was also related to current depression (p = 0,016), as well as to other serious health problems (p = 0,008) and lack of cognitive reserve (p = 0,016).

The worst self- quality of life in elderly people with HIV was also attributed to the additional effects of age and HIV.

The Impact of Bringing HIV on Aging and the Major Depression

"Several of these predictors are highly amenable to proper screening and treatment," the researchers note. "For example, major depression was arguably the most reliable prognosis of adverse functional outcomes in our older cohort of HIV +. These findings highlight the need to track older HIV + adults for depression symptoms, since depression can disrupt the performance of important and potentially remediable arias activities. "They note that the best results are seen in people who are treated with antidepressants and psychotherapy.

The researchers also highlight the association between cognitive reserve and daily function. "This evidence suggests that in adults infected with HIV the lower cognitive reserve may interfere with the adaptive ability to engage in alternative brain networks and / or initiate alternative brain networks and / or initiate the use of compensatory strategies when encountering problems in their daily lives, resulting in incapacity. "


** without coherent results in the search for meaning. *** no resus coherent in the search for meaning. **** Research on AIDS in Women (Woman .... Married Single ... Read this and GIVE YOUR SCREAM) Strange my name because I searched the net and found this definition many times:
Translated by Cláudio Souza in 01 / 0 / 2018 of Original In Double Trouble: Daily Function And The Impact Of Old Age And HIV - Posted On 2012
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