"Based on previous studies in other areas of health, it was not surprising, but perhaps disappointing, given that almost half of people living with HIV are women," said study author Dr. Mirjam Curno, who did the analysis while working as editor-in-chief of The Journal of the International AIDS Society, he said by email.Research in areas such as heart disease, cancer and depression has also had historically low female participation, as well as advanced human trials testing experimental drugs, note Curno and colleagues in the Journal of Acquired Immune Deficiency Syndromes. While it may make sense to have fewer women in studies focused on diseases that disproportionately affect men, the survey results may ignore specific genders, harms or benefits when the proportion of men and women in the study is extremely different from what happens in the real world, said the senior study author Dr. Shirin Heidari by email. That's because, even when the disease is the same, women can have different symptoms than men and respond in unique ways to the treatments being tested. "Failing to systematically study gender and gender differences in health research leads to less evidence-based medicine for one sex or another," said Heidari, who is chairman of the gender policy committee for the European Association of Science Editors. Analysis of gender disparities in HIV trials included more than 500 studies published in prominent medical journals over several decades. A limitation of the analysis is that, by relying on published work, it cannot capture any differences in the gender composition of more recent essays that have not yet been completed, the authors acknowledge. It is possible that at least some studies in the analysis were not done to favor men, but ended up enrolling fewer female participants due to obstacles that can disproportionately affect women, such as lack of child or elderly care or limited transportation or the time to participate, noted Mary Foulkes, a biostatistics researcher at George Washington University in Washington, DC An unanswered question by the analysis is why eligible women may have decided not to participate, Foulkes, who was not involved in the study, said by email. Sometimes, the criteria for enrollment in the trial can be too restrictive to enroll enough women, for example, prohibiting pregnant women, breastfeeding women or women of childbearing age. In the past, eligibility criteria have excluded a large number of women, even in HIV tests designed to study female patients, noted Dr. Monica Gandhi, HIV specialist at the University of California, San Francisco. Under-representation of women in HIV tests may mean that the findings are of limited use in the treatment of female patients, said Gandhi, who was not involved in the study, via email. "When I care for an HIV-infected woman in my clinic, I don't know if this new and exciting treatment or strategy applies specifically to her if the study doesn't include enough people in this or that study that look like her," said Gandhi. SOURCE: bit.ly/1JKDP44 Acquired Immunodeficiency Syndromes Diary, online September 8, 2015 (Reuters Health) -By Lisa Rapaport
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And it was not within a "comfort zone"! This is a story that only I have to tell!
I was the first individual, a CPF, not a CNPJ to, in quotes, “Slap my face”!
For all that I lived, it all happened in a period still troubled by prejudice and, yes, there were prices to be paid.
The currency has always been that of social exclusion and I have even hesitated between continuing or not!
The great “IT” of all this is that without this work, I would have nothing left but leisure and I would certainly not endure it. I have a need to be productive.
We are Borg!
If not bored by the empty hours, at least by suicide due to the absolute lack of purpose that my life would have and the terrible impression of parasitosis that would come to affect me. So, I couldn't stop.
I had the opportunity to accomplish many things and, on the other hand, I missed several opportunities to do more, with a deeper and better reach.
Not everything is as desired. Let it rain (Guilherme Arantes)!
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Hi! Guys, thanks for getting this far! Your attention and interest is our greatest interest, we work here, me and mara, in order to inform you, make some clarity in some nebulous points of "all of this".
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