Injectable Antiretrovirals Every 8 Weeks Generate Great Results

You are in Home => AIDS and Work => Injectable Antiretrovirals Testing Proves Safety
?>
First Hand Injectable Antiretrovirals on 2016

I published about studies on 2016 Injectable Antiretrovirals in the article whose header I published above and the excerpt pasted below.

From 2016 Matter

Click to see full image

Injectable Antiretrovirals

Monthly medication
The End of a Long Winter for Many? I've had to live like this

De Maintenance therapy with cabotegravir and rilpivirine Injectable Antiretrovirals works equally well when given monthly or every two months.

A combination of two injectable antiretrovirals, cabotegravir and rilpivirine, is equally effective in maintaining viral suppression when given once a month or every two months, the companies developing the long-acting regimen announced.

"The results from the ATLAS-2M study mean that people living with HIV can maintain viral suppression with six total treatments per year instead of one daily 365 oral treatment per year," said Kimberly Smith, MD, head of research. and global development of ViiV Healthcare.

Tests had evaluated bimonthly injection after certainty in monthly therapy as safety!

😍😍😍

The formulations ViiV integrase injectable antiretrovirals, Cabotegravir, in addition to Janssen non-nucleoside reverse transcriptase inhibitor, Rilpivirine (sold in tablet form as Edurant) have been studied in people who switched from standard oral antiretroviral therapy with undetectable viral load to those who started HIV treatment for the first time.
As reported at this year's Conference on Retroviruses and Opportunistic Infections, results from the ATLAS Phase III study showed that 92,5% of people randomly assigned to switch to the injectable regimen had undetectable HIV (less than 50 copies) 48 weeks later, as well as 95.5 % of those who remained in their oral regimen.

I see here a possible hypothetical minority in the damage to the labor relationship, if there is anything left of it !!! (…)

Similarly, the FLAIR study showed similar rates of viral suppression in people new to treatment, 93,6% and 93,3%, respectively.

In both studies, treatment with injectable cabotegravir and rilpivirine was generally safe and well tolerated, and serious adverse events were rare.

Most Common Reaction Was Injection Site Pain 😉

The most common side effects were injection site reactions such as pain and swelling, but these were typically mild to moderate and decreased over time.

The results of the study presented at this summer's AIDS Society International Conference on HIV Science in Mexico City showed that people taking injectables reported a high level of satisfaction with treatment and preferred it to oral medicines. daily.
In these studies, cabotegravir and rilpivirine were administered by health care providers as two separate intramuscular injections, preferably in the buttocks.

Participants were asked to return to the clinic each month within a seven-day window. Adherence was good in both studies, with almost all receiving monthly treatment within this window.

However, returning to a clinic for injections every month can be inconvenient, and receiving treatment less often would be attractive.

The ATLAS-2M phase III study was a direct comparison, in which participants were randomly assigned to receive cabotegravir and rilpivirine injections every four weeks or every eight weeks.

They had no history of previous treatment failure. 😯🙄😔

This international study included 1.045 people with HIV who were on their first or second antiretroviral regimen, had viral suppression for at least six months and had no history of previous treatment failure.

ViiV and Janssen announced in press releases that the study achieved its primary goal by showing that the efficacy of the injectable cabotegravir / rilpivirine combo was similar at 48 weeks, regardless of whether it was administered once a month or every two months.

In other words, cabotegravir / rilpivirine administered every eight weeks was found not to be inferior to administration every four weeks.

The companies did not provide viral suppression rates or other detailed data at the time, indicating that they would be presented at an upcoming scientific conference.

“We are excited to report that for the first time since the HIV / AIDS epidemic began more than 30 years ago, our ATLAS-2M study has shown that it is possible to maintain HIV suppression with an injectable regimen containing two medicines given every two years. months, ”said Smith.

"Approval of this regime would mark a significant change in the HIV treatment paradigm."

In the wake of this, on 2017, I published it (controversial theme inside this really hard head of mine) Injectable PrEP may be on its way!

And Because History Matters, the Beginning of Study

Ads

Related Publications

Comment and Socialize. Life is better with friends!

This site uses Akismet to reduce spam. Learn how your feedback data is processed.

Automattic, Wordpress and Sorositivo.Org do everything in our power with regard to your privacy. And we are always improving, improving, testing and implementing new data protection technologies. Your data is protected, and I, Claudio Souza, work on this blog 18 hours or day to, among many other things, ensure the security of your information, since I know the implications and complications of past and exchanged publications. I accept the Privacy Policy of Soropositivo.Org Read All in Privacy Policy

Your opinion is very important!

Would you like to give your opinion about Blog Soropositivo.Org?

If you wish, please provide your email, so we will send you a reply.

Thank you. We welcome your feedback and will return soon

Whatsapp WhatsApp Us
Need to talk? There are three people here providing volunteer services within their means.
error: Content is protected !!